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Comparative studies between Zepbound and other GLP-1 receptor agonists provide further context for United Healthcare's decision-making process. While drugs like Ozempic and Wegovy have already gained broad insurance coverage, direct comparisons between these medications are limited but growing. Research published in peer-reviewed journals has begun to explore the relative efficacy and side effect profiles of these drugs. For instance, a study published in the "New England Journal of Medicine" found that while all three medications demonstrated significant weight loss, Zepbound may offer advantages in certain subgroups of patients.

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